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cellular processes
biological diagram
genetics
molecular biology
gene regulation
The image depicts a biological regulatory loop involving the proteins PER and TIM. CLK and CYC activate the transcription of per and tim genes, resulting in per and tim mRNAs. PER and TIM proteins form a complex. DBT modifies PER. The PER-TIM complex inhibits CLK-CYC activity, thus inhibiting the transcription of per and tim. The crossed-out PER and TIM proteins indicate where the loop may be disrupted or modified.
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